The Lancet

25th March 2017

Report: Global increase in drug-resistant TB threatens to ruin efforts to eradicate the disease

Although a small number of repurposed and new drugs have recently become available to treat drug-resistant TB (including bedaquiline, delamanid, and linezolid), the authors warn that […]
17th January 2014

TB patient treatment

Patients with incurable and highly infectious tuberculosis (TB) were being routinely discharged from hospital to die at home, putting friends, family and people in tehir community […]
17th January 2014

Long-term outcomes of patients with extensively drug-resistant tuberculosis in South Africa: a cohort study

Long-term treatment-related outcomes in patients with extensively drug-resistant (XDR) tuberculosis are unknown. We followed up a cohort of patients to address knowledge gaps. Download article The […]
1st November 2010

Xpert TB diagnostic highlights gap in point-of-care pipeline

Recent unprecedented efforts have led to an expanded tuberculosis diagnostic pipeline, and, in September, publication of the performance of Xpert MTB/RIF in a large multicentre trial […]
19th May 2010

XDR tuberculosis in South Africa: old questions, new answers

In The Lancet today, Keertan Dheda and co-authors present an interesting report about early treatment outcomes of extensively drug-resistant (XDR) tuberculosis (resistant to isoniazid, rifampicin, any […]
1st May 2010

Early treatment outcomes and HIV status of patients with extensively drug-resistant tuberculosis in South Africa: a retrospective cohort study

Data from Kwazulu Natal, South Africa, suggest that almost all patients with extensively drug-resistant (XDR) tuberculosis are HIV-positive, with a fatal outcome. Since, there are few […]
1st May 2010

Multidrug-resistant and extensively drug-resistant tuberculosis: a threat to global control of tuberculosis

Although progress has been made to reduce global incidence of drug-susceptible tuberculosis, the emergence of multidrug-resistant (MDR) and extensively drug-resistant (XDR) tuberculosis during the past decade […]
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