News

Professor Keertan Dheda at the 2017 American Thoracic Society Conference in Washington DC

Congratulations to Professor Keertan Dheda who delivered a Keynote address at the 2017 American Thoracic Society Conference in Washing DC that was attended by ~17000 people. The keynote address is an unopposed lecture of approximately 60 minutes, when no other parallel sessions or lectures are running, that recognizes leading international scientific excellence in a particular field of pulmonary medicine.  Four sets of keynote lectures were delivered during the Conference, one of which was by Anthony S. Fauci, Director of National Institute of Allergy and Infectious Diseases (NIAID).  A certificate of commendation was awarded to Prof Dheda at the end of the lecture and the event was covered in the American local news.

Pro Keertan Dheda interviewed on SAfm

SAfm, Morning talk, 1 May 2017

Download the m4a file 9MB

Tuberkulose: Nuwe medisyne bring hoop

Tiener ontvang nuwe middle teen TB

Download article Die Burger, 25 Maart 2017

Keertan Dheda interviewed on BBC Newsday

BBC Newsday, 24 March 2017

Download the mp3 file 4.6MB

World TB Day

Mail and Guardian, 24-30 March 2017

Read more A time to accelerate the pace towards a TB – free South Africa
Read more SA’s TB think tank puts the county’s brightest minds at helm of its TB- response
Read more A sister dedicated to TB

Latest transmission patterns for drug resistant TB pose a new challenge

The emergence of drug resistant tuberculosis has resulted in scientists taking a more aggressive and urgent approach to research into the development of the disease.

Read more The Conversation, 24 March 2017

Tot 40 000 Suid-Afrikaners kana an MDR-tuberkulose ly

Read more Netwerk24, 24 Maart 2017

Resistance risk for new TB drugs, claims study

According to the report in Lancet respiratory medical journal, although tuberculosis control has been effective in some regions of the world due to small number of repurposed and new drugs that have become available recently to treat drug resistant TB ...

Read more The Asian Age, 24 March 2017

Incurable TB: Patients die without dignity

New tuberculosis (TB) infections have declined around the world – everywhere except sub-Saharan Africa. And the explosion of drug-resistant TB strains in South Africa, and other countries, have led to some patients being diagnosed with totally drug-resistant TB (TDR-TB).

Read more Health-E News, 24 March 2017

Global rise of multidrug resistant tuberculosis threatens to derail decades of progress

New antibiotics are becoming available for the first time but without accurate diagnostics, clear treatment guidelines, and improved control efforts, their effectiveness could be rapidly lost.

Read more Medical News Today, 24 March 2017

South Africa: Latest Transmission Patterns for drug Resistant TB Pose New Challenge

The emergence of drug resistant tuberculosis has resulted in scientists taking a more aggressive and urgent approach to research into the development of the disease.
As the number of drug resistant TB cases has continued to rise, so has the need for rapid diagnosis, new treatment and new strategies that could help contain the disease.

Read more East African Business News, 24 March 2017

Emerging epidemic of multidrug- resistant TB ‘threatens decades of progress’

The global fight to eradicate tuberculosis (TB) is at a critical crossroads, a new report warned today.

Read more Humanosphere, 23 March 2017

Drug-resistant TB strains threatening fight against disease

A new report published in UK medical journal‚ The Lancet‚ ahead of World TB Day on Friday‚ revealed that approximately one in five cases of TB are now resistant to at least one major anti-TB drug and approximately five percent of all cases of TB are classed as multi-drug resistant(MDR) or extensively drug-resistant(XDR).

Read more Times LIVE, 23 March 2017

Superbug tuberculosis threatens global control efforts

TB kills more people each year than any other infectious disease, including HIV and AIDS. In 2015 alone, it is estimated to have killed 1.8 million people, according to the World Health Organization (WHO).

Read more CBCNews, 23 March 2017

Decades of TB progress threatened by drug-resistant bacteria, warns experts

Rise of multi-drug resistant strains of tuberculosis could derail global efforts to eradicate the disease, according to a new report.

Read more The Guardian, 23 March 2017

Rise of multidrug resistant TB ‘threatens to derail decades of progress’

Tuberculosis is becoming increasingly resistant to drugs worldwide which threatens to derail decades of progress, a report warns.
Read more iNews, 23 March 2017

Media reports

Read more  23 March 2017

Rise of superbug tuberculosis hampers global control efforts

Rising rates of superbug tuberculosis (TB) are threatening to derail decades of progress against the contagious disease, experts said on Thursday, and new drugs powerful enough to treat them are few and far between.

Read more Reuters, 22 March 2017

Prof Keertan Dheda interviewed on eNCA

Watch video eNCA, 17 March 2017

Study discovers new TB strain in South Africa

Prof Dheda interviewed on SABC news, 28 February 2017

Read more

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Highly infectious strain of TB

Prof Dheda interviewed on The Koketso Sachane Show (26 February 2017, 11:50pm)
Download the m3 file 11MB

State hospitals discharging patients with incurable XDR TB

Prof Dheda interviewed on Cape Talk Radio (26 February 2017)
Download the m4a file 5.35MB

Shocking: Several TB strains now incurable, say local researchers

The rise of drug-resistant tuberculosis has taken a new, horrifying turn. According to scientists, as a result of patients not finishing their treatments for tuberculosis (TB), several strains of the disease have become not just drug-resistant, but incurable!

Read more health24, 7 February 2017

 

Incurable Tuberculosis being spread

eNCA- Channel 403 DSTV, 7 February 2017

DNA test uncovers hidden TB cases

Tuberculosis has killed more than a billion people over the last two centuries. A new UCT-led study had the myriad undiagnosed cases of the highly infectious disease in its crosshairs.
It’s estimated that 30–40% of TB cases globally are never diagnosed. Typically, TB tests happen only when prospective patients approach a clinic or hospital, which leaves many potential cases flying under the radar. This makes containing the spread of the highly infectious disease nigh impossible.
Read More UCT: Today's news, 9 February 2017
Read More Lancet, Infectious Diseases, 4 January 2017

Concern over sharp increase in drug-resistant TB cases in South Africa

CAPE TOWN – A University of Cape Town researcher says there's been a sharp increase in the number of drug-resistant Tuberculosis (TB) cases being reported.
Globally, one person dies of TB every three minutes.
An estimated 35,000 multidrug-resistant Tuberculosis cases were recorded in South Africa in 2014.
– Prof Dheda interviewed by EWN
Read More EWN, 6 February 2017

TB: New incurable strains

The rise of drug-resistant tuberculosis has taken a new, horrifying turn. While various strains of TB, with varying degrees of resistance to drugs, have wreaked havoc on South Africans, a new strain of TB has been found to be simply incurable.
These sobering findings were published in Lancet Respiratory Medicine by a UCT-led team of scholars, who tracked more than 237 patients with extensive drug-resistant TB (XDR-TB).
Read More UCT: Today's news, 30 January 2017

Address poverty, HIV to stem TB

The rise of incurable tuberculosis (TB) underscores the need to address poverty, overcrowding and the HIV epidemic in Africa, experts say.
Read more Cape Times, 30 January 2017

Fears over rise of incurable TB

URGENT action, including rapid diagnosis, better access to medication, improved home-based care and more community-stay facilities for patients, is crucial in addressing the rising transmission and infection rates of incurable TB.
Read more Pharmacy Choice, 30 January 2017
Read more Diamond Field Advertiser, 30 January 2017

New TB test could help curb disease

A recent landmark trial showed 53% more patients initiated therapy for tuberculosis (TB) after a new DNA-based diagnostic tool was used to screen for the disease in more that 2261 individuals.
Read more Cape Times, 26 January 2017

DNA sequencing used to track transmission of incurable TB in South Africa

Cape Town | TB researchers suggest that urgent action, including rapid diagnosis, wider access to newer and repurposed drugs, and bolstering home-based care and building long term community stay facilities for patients are pivotal in addressing the rising transmission and infection rates of incurable TB.
Read more SAMRC MEDIA, 23 January 2017

DNA-based detection test improves battle strategy against TB by finding undiagnosed cases in the community

Cape Town |  A recent randomized controlled trial revealed that 53% more patients initiated therapy for tuberculosis (TB) after a new diagnostic tool (GeneXpert MTB/RIF) was used to screen for TB in more than 2 261 individuals in the community.
Read more SAMRC MEDIA, 20 January 2017

TB alert for young children

AN AUDIT conducted by the City shows that 42 percent of children exposed to TB patients have not been screened for the disease.
Read more Cape Times, 10 November 2016

LAMTest_large

UCT Study: Low-cost urine TB test reduces TB death-rate

A rapid, and simple to use, low-cost urine sample to test for TB at the bed-side of HIV patients both able and unable to produce sputum, reduced the TB death-rate of patients with advanced HIV. TB treatment can be initiated quicker than if diagnosed using current diagnostic tools

Read more UCT Faculty of Health Science, 15 March 2016
Read more UCT: Today's news, 16 March 2016

urine_test_for_tb

Urine test improves detection of TB

Tuberculosis often lies undetected in the very patients it is most likely to kill: HIV positive patients. But a urine test could change that.

Read more The Times, 27 January 2016

Prof_Keertan_Dheda

Six new UCT fellows announced

At a ceremony on Tuesday 13 October, UCT announced the names of six new fellows – permanent academic staff who are being recognised by UCT Council for distinguished academic work.

Read more UCT: Today's news, 16 October 2015

The rise of antibiotic resistance



Newsroom, 21 September 2015

when_to_see_a_GP

Coughs: When to see a GP

YOU have a relentless, hacking cough that just won’t go away, but you don’t think it’s anything serious. It could be because of the change of season or the recent cold snap that gripped many parts of the country; you must have picked up a bug somewhere. This is what you tell yourself – but you start feeling a bit worried when weeks later you’re still coughing.

Download article You, 7 May 2015

shack-fires

Cape Town residents suffer smoke inhalation

CAPE TOWN - Not being able to breathe is a trauma many Cape Town residents have experienced in the last week. From regular shack fires to the recent fires which spread across the Cape Peninsula, it's a reality for many.
Read more Enca, 10 March 2015

MDR/XDR-TB Conference, 10 – 12 October 2014, UCT

Presentations for the conference are available for download.
Please visit www.xdrtbconference.co.za

Dying to Breathe

Carte Blanche, 7 September 2014, People with severe asthma often live a life of debilitating solitude and cannot enjoy the outdoor activities many take for granted. But an innovative new procedure called bronchial thermoplasty is set to change lives. [...Watch video]

Keertan+Dheda+xxx

Prof Keertan Dheda – Man with a mission

WHEN Keertan Dheda grew up in Durban’s Casbah suburb in the 1970s, dinner table conversations were dominated by the numerous doctors in his extended family. The son of a tailor and a housewife, he longed to join the ranks of the medical fraternity, driven by the noble idea of healing broken bodies.

Read more Business Day Live, 30 June 2014

Water Borne diseases and contaminated water in Bloemhof

Tuberculosis+xray

No cure for some TB patients

There are patients who have incurable and infectious Tuberculosis who are being discharged from hospitals as they cannot be treated.
Read more Times Live, 11 June 2014

Keertan-Dheda-Nicky-O-Wieland-Gevers

Prof Keertan Dheda receives the Oppenheimer Fellowship

UCT is delighted that one of its academics, Prof Keertan Dedha, is the 2014 recipient of the Oppenheimer Fellowship, the Oppenheimer Trust’s premier award with a monetary value of R1,5 million.
Read more UCT Faculty of Health Sciences, 3 June 2014

260514_tb_4

South Africa: The TB Time Bombs

"My life has stopped. I don’t want anyone to go through what I’m going through,” 36-year-old Kirt tells me through the facemask that holds back the microscopic droplets that escape from his mouth as he coughs and speaks.
Read more Pulitzer Center on Crisis Reporting, 2 June 2014

UCT forges ahead on TB research

UCT researchers have been nominated for BHP Billiton Awards for their work in the fight against tuberculosis, from using satellite tracking to identify "super spreaders", to proving that clinics can diagnose the disease within as little as two hours.
Download article Weekend Argus, 31 May 2014

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Return of the ‘White Plague’: Fears over the rise of ‘incurable’ TB

"Sometimes I ask myself, why me? Why did this have to happen again?" says 31-year-old Andile from the Khayelitsha township in Cape Town, South Africa. "But the problem is I could have got it anywhere, on the bus, in a taxi, in my work. It's everywhere."
Read more CNN, 28 May 2014

UCT finalists compete for annual NSTF-BHP Billiton Awards

Eleven UCT researchers have been selected as finalists for the prestigious NSTF-BHP Billiton Awards for 2013/14. The national awards celebrate outstanding contributions to Science, Engineering, Technology and Innovation (SETI) in South Africa. With 11 out of a total of 56 finalists, this is an excellent showing for our academic community, says Prof Danie Visser, Deputy Vice-Chancellor for Research.
Read more UCT: Today's news, 21 May 2014

10% of adults currently suffering from asthma are unable to control it

Download article Netcare Health, Issue 1 2014

Management of drug-resistant tuberculosis

Download Provincial TB Directorates

Superspreaders: Tracking tuberculosis

Tuberculosis (TB) is still a huge problem throughout the world. South Africa is particularly hard hit by the disease. It is one of only two countries where incidence of TB is still rising.
Read more BBC News Health, 27 March, 2014

New tech offers hope of tackling TB in South Africa

Face masks incorporating satellite tracking and cough samplers are among the new technologies being tested to help researchers in South Africa try to control the epidemic of drug-resistant tuberculosis.
Read more Sci Dev Net, 22 March, 2014

Patients with deadly TB released in South Africa

The spread of a virtually untreatable form of tuberculosis in South Africa is being fueled by the release of infected patients into the general community, according to a new study.
Read more The Malta Independent, 22 January, 2014
Download article The Journal, 20 January, 2014

Long-term outcomes of patients with extensively drug-resistant tuberculosis in South Africa: a cohort study

Long-term treatment-related outcomes in patients with extensively drug-resistant (XDR) tuberculosis are unknown. We followed up a cohort of patients to address knowledge gaps.
Download article The Lancet, 17 January, 2014
Download press release UCT press release
Download press release The Lancet press release

SA grapples to mitigate drug-resistant TB – study

LONDON - Patients with contagious and highly drug-resistant tuberculosis (TB) are being routinely discharged from hospitals across South Africa, exposing others in their communities to potentially deadly infections, researchers said on Friday.

Read more eNCA, 17 January 2014

TB patient treatment

Patients with incurable and highly infectious tuberculosis (TB) were being routinely discharged from hospital to die at home, putting friends, family and people in tehir community at risk of catching teh disease, according to a South African study published in science magazine th Lancet today.
Download article Business Day, 17 January 2014

Do high rates of empirical treatment undermine the potential effect of new diagnostic tests for tuberculosis in high-burden settings?

In tuberculosis-endemic settings, patients are often treated empirically, meaning that they are placed on treatment based on clinical symptoms or tests that do not provide a microbiological diagnosis (eg, chest radiography).
Download article The Lancet, 15 January 2014

Tackling drug-resistant TB in London

Health experts are trying to tackle an increase in a highly infectious drug-resistant form of TB which could leave London on the cusp of a TB epidemic. Scientists have uncovered mutations of the bacteria that are rapidly becoming resistant to all known antibiotics and medications.
Read more BBC News, 6 January 2014

MRC_award

Unit wins prestigious MRC award

In his address to MRC award and grant winners at a prestigious ceremony in Cape Town, outgoing MRC Chairperson Professor Lizo Mazwai described the South African Medical Research Council (MRC) as “richer, more focused, more efficient and better placed to deliver a healthy nation through research.”
Download article Medical Research Council of South Africa

Top news – Media Reports

Download report 31 October 2013

Faster TB test fails to improve prognosis

PARIS - An on-the-spot sputum test for tuberculosis works better than the commonly-used, 125-year-old microscope method, but did not reduce illness in a southern African trial, a study reported on Monday.

Read more eNCA, 28 October

w460

Sputum Test May not Hold Key to TB Eradication

An on-the-spot sputum test for tuberculosis works better than the commonly-used, 125-year-old microscope method, but did not reduce illness in a southern African trial, a study said Monday.
Read more The Nation, 29 October 2013
Read more naharnet, 28 October 2013
Read more menafn.com, 28 October 2013
Read more Enca, 28 October 2013
Download article Feasibility, accuracy, and clinical effect of point-of-care Xpert MTB/RIF testing for tuberculosis in primary-care settings in Africa: a multicentre, randomised, controlled trial The Lancet, 28 October 2013
Download article Point-of-care diagnostics for tuberculosis elimination? The Lancet, 28 October 2013

Point-of-Care Xpert MTB/RIF Testing Feasible in Primary Care

Point-of-care Xpert MTB/RIF tuberculosis testing is associated with more patients getting same-day diagnosis and having same-day treatment initiation but does not result in improved tuberculosis-related morbidity, according to a study published online Oct. 28 in The Lancet.
Read more Doctors Lounge, 28 October 2013

New ultrasound technology for Groote Schuur Hospital

Incurable cases of TB

Prof. Dheda interviewed on Power FM
Download MP3 file 2.84 MB

Mandela’s condition ‘very serious’

A man sells goods on June 11, 2013 on the streets of Johannesburg in front of a newspaper billboard reading "Don't let Madiba go - Qunu villagers." Nelson Mandela remained another day in hospital with no reports of any improvement in his condition which South African President Jacob Zuma described as "very serious" but "stabilised."
Read more Bangkok Post, 12 June 2013

New technology for cancer biopsies at Groote Schuur

Download article Cape Argus, 3 June 2013
Download article Die Burger, 6 June 2013

New asthma treatment

The new technology, which was unveiled at Groote Schuur Hospital for teh first time in Africa yesterday, is a minimal brochoscopic procedure that heats the wall of teh airways ina controlled manner opening them up.
Download article Cape Argus, 26 April 2013

TB-NEAT: TB diagnostics in low-resource settings

Watch this informative video as uploaded to YouTube by EDCTP.

Mandela treated for pneumonia

Read more The Australian, 1 April 2013
Read more The Jakarta Globe, 31 March 2013
Read more Hurriyet Daily News, 30 March 2013

tuberculosis

SA pays high price for drug resistant TB

According to a study a case of extensively drug resistant tuberculosis (TB) costs South Africa about $26 392 (R234 516.67) to treat, which is four times that of drug resistant TB, which costs $6 772, and a 103 times more than drug sensitive TB, which costs $257.
Read more Times LIVE, 19 January 2013

New divisional heads appointed

Three new top appointments at UCT's Department of Medicine – all black staff – are proof that the university is well on its way to becoming "a home for all South Africans"...
Download article

Unit wins more awards at latest Thoracic Society meeting

The run of good fortune has continued as the Lung Infection and Immunity Unit made a clean sweep of the original research awards at the combined national South African Thoracic and Critical Care societies meeting in Sun City on the 28th of August 2012.
Read more

three_awards

Unit scoops three awards

Three young rising stars from the UCT Lung Infection and Immunity unit, headed by Professor Keertan Dheda, are the recipients of three prestigious awards. All three awards recognise completed or proposed research in the ongoing fight against TB.
Read more

van_zyl_grad

Well done, Richard!

The Lung Infection and Immunity Unit would like to express its heartfelt congratulations and joy at the recent graduation of PhD student Dr. Richard van Zyl-Smit who successfully obtained his degree. Richard is a pulmonologist who conducted studies about the TB-specific host immune responses in the lung and how they are modulated by tobacco smoke.

dheda-award

Unit head nominated for 2012 NSTF-BHP Billiton award

A host of UC scholars and units have been nominated for the 2011/12 National Science and Technology Forum-BHP Billiton awards. This year, the NSTF celebrates its 14th Awards, which recognise, acknoledge and promote excellence in the South African research and development community.
Download article Monday Paper, 21 May – 3 June 2012

The 2011 Sixth EDCTP Forum

The 2011 Sixth EDCTP Forum was held in Addis Ababa and was attended by Professor Keertan Dheda and Dr. Grant Theron from the Unit. Several important activities and discussions at the Forum focused on scientific development and capacity development in Africa (see interview with Keertan). The Forum Report and the Forum Video can be viewed at the following links. 9–12 October 2011

Leading from the front

Three UCT research facilities have been named as centres of excellence by the African Network for Drugs and Diagnostics Innovation.
Download article Monday Paper

Tony-Segal-and-staff-web

Professor Segal, Director at the Centre for Molecular Medicine in London, visited the unit in January 2012

From left: Professor Dheda, head of the Lung Infection and Immunity Unit,
Dr Grant Theron, Prof Anthony Segal, Dr Anke Binder, Dr Jonny Peter,
Lameze Fredericks, Anil Pooran, Malika Davids

dheda0701

Lung Infection and Immunity Unit project

In a project led by Professor Keertan Dheda, a prototype TB test strip was successfully demonstrated and there are plans to further develop the intellectual property. Prototype development is nearing completion and a spin-off company, Antrum Biotechnologies (Pty) Ltd, has successfully attracted funding from the Department of Trade and Industry’s SPII to pursue the next stage. More significant funding is also being raised to take the product to market.

davids_malika

Student piques interest with her TB findings

Malika Davids, a doctoral student in UCT's Lung Infection and Immunity Unit in the Department of Medicine, certainly had her fellow delegates sitting up and taking notice of her poster presentation at the recent World Immune Regulation Meeting V in Davos, Switzerland.
Read more UCT: Today's news, 8 June 2011

2nd-place-Elite

Sports achievement for Lung Unit member

Russell Mains, a member of the Lung Unit, and his team won second place in the Elite section at the SA National Darts Championship held at Kibler Park in Gauteng in July 2011. We congratulate Russell and his team for their fine achievement in this highly competitive category.

Nuwe masjiene kan MDR-TB gou raaksien (New MDR-TB diagnostic tool)

Splinternuwe masjiene wat vir die eerste keer middelweerstandige tuberkulose (MDR-TB) in staatshospitale kan diagnoseer,isdeurdiedepartementvangesondheid aangekoop.
Download article Die Burger, 15 April 2011

Global TB research body honours UCT professor

Dr Keertan Dheda (right), Associate Professor of Respiratory Medicine at the University of Cape Town, receives the 2010 Union Scientific Award, bestowed by the International Union Against Tuberculosis and Lung Disease, from Dr Michael Kimerling of the Gates Foundation.

Dr Keertan Dheda (right), Associate Professor of Respiratory Medicine at the University of Cape Town, receives the 2010 Union Scientific Award, bestowed by the International Union Against Tuberculosis and Lung Disease, from Dr Michael Kimerling of the Gates Foundation.

Dr Keertan Dheda, Associate Professor of Respiratory Medicine at the University of Cape Town, is the recipient of the 2010 Union Scientific Award, bestowed by the International Union Against Tuberculosis and Lung Disease (IUATLD). The annual global award honours a researcher under the age of 45 who has made an outstanding contribution to the field of tuberculosis and/or lung disease.

Dr Dheda’s research focuses mainly on poverty-related lung disease, including TB, HIV and pneumonia. The IUATLD said in its citation for Dr Dheda: “He is particularly recognised for his expertise on drug-resistant TB and is considered one of the experts in South Africa on TB drug-resistance, providing frequent advice and consultation nationally on drug-resistant cases … Of particular note, Dr Dheda has co-developed a programme offering training and clinical services related to drug-resistant TB at the two designated XDR-TB hospitals in the Northern and Western Cape Provinces of South Africa … His work has influenced decisions or recommendations made by the South African National TB Programme and other leading international TB and health organisations. He is internationally recognised for his work in TB diagnostics, TB immunology and drug-resistant TB, and holds a patent related to new diagnostic technologies for which he has received a grant from the South African Department of Science and Technology to develop further.”

Dr Dheda is Associate Professor of Respiratory Medicine and Director of the Lung Infection and Immunity Unit in the Department of Medicine at UCT. He also holds a faculty position at the Centre for Infectious Diseases and International Health at University College London, as part of the UCL-UCT Diseases of Poverty Collaboration Initiative, which aims to facilitate the training of African post-graduate students to improve global health.

The mission of the IUATLD is to bring innovation, expertise, solutions and support to address health challenges in low- and middle-income populations. Its scientific departments focus on tuberculosis, HIV, lung health and non-communication diseases, tobacco control and research

Watch the movie: Opening of the World Conference

Collapsed lungs

SABC Interview
Download wav file 5 MB

XDR-TB

Radio Interview on SAFM
Download MP3 file 29.9 MB

Pneumonia and COPD

Keertan Dheda interviewed on SAFM, 23 November 2011
Download MP3 file 20.2 MB

morris_2010

Xpert TB diagnostic highlights gap in point-of-care pipeline

Recent unprecedented efforts have led to an expanded tuberculosis diagnostic pipeline, and, in September, publication of the performance of Xpert MTB/RIF in a large multicentre trial was heralded as representing a new era in tuberculosis diagnostics.
Download article The Lancet, November 2010

SA Health Workers Getting Deadly TB

UCT researchers have shown that health workers in South Africa are contracting extensively drug-resistent tuberculosis (XDR-TB), the most serious form of the disease that is extremely difficult to treat.
Download article Cape Times, 21 September 2010

TB workshop commentary

The controversial question of whether or not to incarcerate patients with drug-resistant tuberculosis came under the spotlight at a workshop held at the Faculty of Health Sciences from 3 to 5 September.
Download article Monday Paper, 13-26 September 2010

mtpi_comm

Keertan Dheda serves on American Thoracic Society MTPI committee 2009-2010

Left to right. BACK ROW: Ed Chan, Stephen Gordon, Keertan Dheda, Charles Feldman, Mark Metersky;
FRONT ROW: Sam Moskowitz, Adithya Cattamanchi, Carol Hamilton, Marcos Restropo, Scott Evans, Adrian Rendon

lung_infect_pic2

Dr Richard van Zyl-Smit

First prize: The Lung Infection and Immunity Unit’s Dr Richard van Zyl-Smit won best PhD oral presentation at the 2008 Medical Research Council Research Day for his work on developing new rapid tests for diagnosing TB.

Multidrug-resistant and extensively drug-resistant tuberculosis: a threat to global control of tuberculosis.

Although progress has been made to reduce global incidence of drug-susceptible tuberculosis, the emergence of multidrug-resistant (MDR) and extensively drug-resistant (XDR) tuberculosis during the past decade threatens to undermine these advances.
Read more The Lancet, May 2010
Download article

Early treatment outcomes and HIV status of patients with extensively drug-resistant tuberculosis in South Africa: a retrospective cohort study.

Data from Kwazulu Natal, South Africa, suggest that almost all patients with extensively drug-resistant (XDR) tuberculosis are HIV-positive, with a fatal outcome. Since, there are few data for the treatment-related outcomes of XDR tuberculosis in settings with a high HIV prevalence, we investigated the associations of these diseases in such settings to formulate recommendations for control programmes.
Read more The Lancet, May 2010
Download article

Infection control ‘urgently needed’ to curb spread of XDR-TB among health care workers

XDR tuberculosis in South Africa: old questions, new answers

In The Lancet today, Keertan Dheda and co-authors present an interesting report about early treatment outcomes of extensively drug-resistant (XDR) tuberculosis (resistant to isoniazid, rifampicin, any fluoroquinolone, and at least one injectable drug: capreomycin, kanamycin, or amikacin) in South Africa.
Read more The Lancet, 19 May 2010

TB_hits_health_workers

TB hits health workers

TB is the most common serious opportunistic infection that HIV-positive South Africans contract. TB patients who are tested for HIV can be put on antiretroviral treatment earlier, which can prevent further opportunistic infections and even death.
“If you don’t treat the HIV you don’t treat the underlying cause, and the patient could get another episode of TB or another infection later on,” Dheda says.
Download article Mail & Guardian, May 2010

World TB Day 2010

The Lung Infection and Immunity Unit of the University of Cape Town would like to join with the rest of the world in commemorating World TB day today, Wednesday the 24th of March, 2010. The Unit would like to take the opportunity to re-affirm its commitment to improving heath care through research, continued development of diagnostic techniques and dedicated patient care. We are also pleased to announce the publication 'Clinical utility of a commercial LAM-ELISA assay for TB diagnosis in HIV-infected patients using urine and sputum samples', published in PLoS ONE today.
Download article PLoS ON, March 2010

Download article Bulletin of UK TB Research, 2010
Download article World TB Day 2010: Eradicating tuberculosis in sub-Saharan Africa needs effective and committed north-south partnerships SAMJ, March 2010
Download article World TB Day 2010 – New innovations are required for enhancing the global fight against Tuberculosis: the ‘Captain of all these men of death’ Tropical Medicine and International Health, March 2010

kissoflife

Kiss of Life for lung-infection research

Thanks to their new Discovery Foundation Academic Fellowships, Dr Hoosain Khalfey and Dr Greg Symons have the funding to continue their potentially ground-breaking studies of lung infections over the next two years.
Download article

Doctor raises questions over TB skin testing

Skin testing for tuberculosis, teh current method used in South Africa as well as in the UK and Canada is being questioned by a top UCT academic.
Download article Argus, 23 October 2009

monday-paper

Success in triplicate for TB researchers

Three specialists at UCT’s Lung Infection and Immunity Unit have won substantial US fellowships for their doctoral studies on tuberculosis.
Download article Monday Paper, 26 October - 8 November 2009

monday-paper2

Researcher puts TB screening to the test

New findings by UCT’s Dr Richard van Zyl-Smit could up-end some widely-held tenets of tuberculosis testing. Based at the Lung Infection and Immunity Unit, Van Zyl-Smit, 36, argues for a new TB-testing regime in a paper published in the American Journal of Respiratory and Critical Care Medicine, aka the Blue Journal.
Download article Monday Paper, 26 October - 8 November 2009